1 00:00:00,430 --> 00:00:06,710 Hello! You have already studied the different glands that are part of the endocrine system, 2 00:00:06,889 --> 00:00:09,949 the glands, the hormone, and the different functions of them. 3 00:00:10,369 --> 00:00:13,509 But now a question comes to your mind. 4 00:00:14,009 --> 00:00:17,550 How does the endocrine coordination work? 5 00:00:17,769 --> 00:00:18,969 We're going to learn it today. 6 00:00:28,739 --> 00:00:33,679 Now please take your notebook, open it up, and after the photocopy I give you in class, 7 00:00:33,679 --> 00:00:38,600 you need to write the title 4.1, How does the endocrine coordination work? 8 00:00:39,359 --> 00:00:47,740 Before I start explaining with a beautiful drawing how does the endocrine system work, 9 00:00:47,740 --> 00:00:54,479 you need to copy three definitions, endocrine cell, receptor and target cell. 10 00:00:54,479 --> 00:01:01,960 Endocrine cells, cells which secrete hormones and release them into the blood stream. 11 00:01:01,960 --> 00:01:09,319 Receptors. Molecules on the cell membrane that binds to specific hormones. 12 00:01:10,219 --> 00:01:15,420 Target cell. Cells that respond to specific hormones. 13 00:01:16,680 --> 00:01:18,659 Have you finished copying? Great. 14 00:01:19,079 --> 00:01:23,840 Now imagine that we have an endocrine cell, which is inside the gland. 15 00:01:23,840 --> 00:01:28,840 We have here a gland that could be the pancreas, 16 00:01:28,840 --> 00:01:37,980 could be, for example, the pituitary gland, could be the thyroid, any gland that you can think about, 17 00:01:38,239 --> 00:01:45,719 okay? This gland has endocrine cells. These cells, that's as we say in definition, release hormones. 18 00:01:46,040 --> 00:01:52,620 The hormones are the triangles which are going to get into the blood capillaries. 19 00:01:52,620 --> 00:01:56,859 when they get into the blood capillaries 20 00:01:56,859 --> 00:01:58,760 they are going to follow 21 00:01:58,760 --> 00:02:00,920 the path of the blood 22 00:02:00,920 --> 00:02:02,400 with the blood stream 23 00:02:02,400 --> 00:02:04,700 inside the plasma 24 00:02:04,700 --> 00:02:06,959 and it's going to travel 25 00:02:06,959 --> 00:02:09,139 along the capillaries 26 00:02:09,139 --> 00:02:10,800 they get to the 27 00:02:10,800 --> 00:02:12,340 arteriole 28 00:02:12,340 --> 00:02:14,139 they get to the 29 00:02:14,139 --> 00:02:16,780 veins, they get to arteries 30 00:02:16,780 --> 00:02:18,300 etc. until 31 00:02:18,300 --> 00:02:20,159 they come to a place 32 00:02:20,159 --> 00:02:21,759 where they need to be 33 00:02:21,759 --> 00:02:28,139 the target cell, the place where there is a receptor on the outer part, on the 34 00:02:28,139 --> 00:02:35,159 membrane, which is the place where they are going out of the plasma 35 00:02:35,159 --> 00:02:42,740 and they are going to fix into the receptor. Imagine that we have this 36 00:02:42,740 --> 00:02:49,800 receptor on the membrane of the target cell. The hormone comes around here and 37 00:02:49,800 --> 00:02:57,960 and says oh this is the place where i need to go and it has the correct shape exactly the same 38 00:02:57,960 --> 00:03:04,599 shape as the place where you need to fix with the receptor that is really really important what 39 00:03:04,599 --> 00:03:12,439 happens if it's not the correct shape then we are in the non-target cell when the hormone reaches 40 00:03:12,439 --> 00:03:21,080 a non-target cell it has a different type of receptor if it comes here it doesn't fit 41 00:03:22,439 --> 00:03:28,919 it's not the place where it needs to be so it's not going to join to the to this cell and it's 42 00:03:28,919 --> 00:03:35,960 going not going to make the action it needs to do so it's only going to get to the target cell 43 00:03:35,960 --> 00:03:43,719 and then start performing the action that it needs to do imagine that we have a second hormone that 44 00:03:43,719 --> 00:03:54,020 is also going along the blood capillaries but has this shape when it reaches this receptor then it's 45 00:03:54,020 --> 00:04:03,219 going to fix it's going to fix and it's going to perform a certain action then this cell will 46 00:04:03,219 --> 00:04:09,879 become a target cell for the red hormone but it's not going to be the target cell 47 00:04:09,879 --> 00:04:17,699 for the green hormone so only one receptor fixes with one hormone and then 48 00:04:17,699 --> 00:04:24,459 start performing the function and you will think what happens later we have a 49 00:04:24,459 --> 00:04:29,459 hormone that is going to get to the target cell what is going to happen next 50 00:04:29,459 --> 00:04:38,220 when the hormone fixes fix with the receptor is going we say to perform a 51 00:04:38,220 --> 00:04:50,790 function the target cell is going to be activated what does this mean it means 52 00:04:50,790 --> 00:04:56,970 that is going to release some protein to is going to start dividing it depends on 53 00:04:56,970 --> 00:05:02,250 the hormones imagine for example the growth hormone what was a function of 54 00:05:02,250 --> 00:05:14,699 growth hormone the function of the growth hormone was to grow the bones so if we have 55 00:05:15,660 --> 00:05:21,660 the growth hormone released getting to the bloodstream and then gets to the bones when 56 00:05:21,660 --> 00:05:28,139 it gets to the bone it's going to activate the bones and the bone cell will start multiplying 57 00:05:28,939 --> 00:05:38,939 dividing and making new cells to make the bone grow. There are also hormones that are going to 58 00:05:38,939 --> 00:05:47,660 inactivate the cell. It's not going always to be a positive action. Imagine that we are growing, 59 00:05:47,660 --> 00:05:53,100 growing, growing and we need to stop. We need a signal for the cell to say hey stop, do not divide 60 00:05:53,100 --> 00:06:00,899 anything else. Do not divide more. That action is going also to be performing hormones. So there 61 00:06:00,899 --> 00:06:07,980 are hormones that will activate cells, hormones that will inactivate cells. I want you now to 62 00:06:07,980 --> 00:06:16,220 think of different examples of how this is going to happen. To have here a gland, draw the gland 63 00:06:16,220 --> 00:06:21,660 or write the name of the gland, write endocrine cell, the type of hormone is going to release 64 00:06:21,660 --> 00:06:27,339 to the blood capillary try to get us the way that hormone has to go by now that you have 65 00:06:27,339 --> 00:06:34,939 studied the circulatory system you should know a little bit about it right the organ that is going 66 00:06:34,939 --> 00:06:41,980 to be the target cell of that hormone and the function that it needs to be done there 67 00:06:41,980 --> 00:06:46,779 it's an exercise so do it on the right side of your notebook 68 00:06:46,779 --> 00:06:58,259 and that's all for today i hope you will understand a little bit the function of 69 00:06:58,259 --> 00:07:04,180 these hormones you also have a video in the aula virtual which tells you more about this 70 00:07:15,600 --> 00:07:19,379 Ha, ha, ha, ha, ha, ha, ha, ha, ha, ha.