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Aparato de Golgi - Contenido educativo
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It is important that translated proteins are delivered to their specific cellular location.
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To accomplish this, the protein is transferred through a series of membrane structures.
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A principal membrane component is the Golgi apparatus.
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The Golgi apparatus is the sorting organelle of the cell.
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Proteins from the rough endoplasmic reticulum are sent to the Golgi.
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As the proteins move through the Golgi apparatus, they are modified and packaged into vesicles.
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Because the Golgi apparatus receives proteins from one location and targets them for delivery
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to a second location, it is sometimes considered the post office of the cell.
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The Golgi apparatus consists of general components.
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The cyst cisterna nearest the endoplasmic reticulum , the medial and trans cisternae,
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the trans-Golgi network.
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Other key players in this process are the proteins being transported and the enzymes
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that modify them.
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Translated proteins are encapsulated in vesicles in the ER.
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A group of these vesicles fuse, and these fused vesicles form the cis cisterna.
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As the protein moves through the stack, it is modified by resident Golgi enzymes at specific
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locations in the apparatus.
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These modifications are important because they provide the signal that determines the
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final destination of the protein.
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So how does the protein move through the Golgi?
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Movement occurs in waves.
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First, the cis cisterna becomes part of the medial Golgi cisternae.
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Behind it, a new cis cisterna is formed by the fusion of vesicles from the ER.
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Meanwhile, one of the medial cisternae migrates and becomes the new trans cisterna.
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Collectively, this process is known as the cismaturation model.
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Proteins are sorted within the transgolgi network.
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Proteins with the same target sequence are destined for delivery to the same location.
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The transgolgi network then buds off into vesicles.
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These vesicles then migrate to their target location.
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These locations include internal organelles, such as the lysosome, the digestive organelle
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of the cell.
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The vesicles can also be targeted to the cell membrane, where the targeted protein can be
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released from the cell for delivery elsewhere in the organism.
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- Subido por:
- Estrella D.
- Licencia:
- Todos los derechos reservados
- Visualizaciones:
- 108
- Fecha:
- 4 de octubre de 2020 - 12:56
- Visibilidad:
- Público
- Centro:
- IES JOAQUIN RODRIGO
- Duración:
- 03′ 28″
- Relación de aspecto:
- 4:3 Hasta 2009 fue el estándar utilizado en la televisión PAL; muchas pantallas de ordenador y televisores usan este estándar, erróneamente llamado cuadrado, cuando en la realidad es rectangular o wide.
- Resolución:
- 480x360 píxeles
- Tamaño:
- 9.10 MBytes